Transcription Factor AP-2 Controls Transcription of the Human Transforming Growth Factor-α Gene

Transforming Growth Factor 1 Stimulates Vascular Endothelial Growth Factor Gene Transcription in Human Cholangiocellular Carcinoma Cells

The expression pattern and functional interaction of proangiogenic factors in human cholangiocellular carcinoma (CCC) have not been fully defined. We therefore investigated the expression of vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)1 as well as their respective receptors in human CCC tumor samples and further analyzed their functional interaction in vitro. E...

Transcription Factor Gene AP-2 Essential for Early Murine Development

Transforming a transcription factor

A transcription factor that regulates skeleton formation in sea urchin embryos has evolved a new domain that is essential for this process.

DAP-2, the Drosophila homolog of transcription factor AP-2

Transcription factor AP-2 is essential for craniofacial, nervous system, and limb development in the mouse. We report here the cloning and expression pattern analysis of DAP-2, the Drosophila homolog of AP-2 family genes. DAP-2 is expressed in discrete regions of procephalic neuroectoderm, the brain, ventral nerve cord, and maxillary segment during Drosophila embryogenesis, and in the brain, op...

Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells.

The expression pattern and functional interaction of proangiogenic factors in human cholangiocellular carcinoma (CCC) have not been fully defined. We therefore investigated the expression of vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)-beta 1 as well as their respective receptors in human CCC tumor samples and further analyzed their functional interaction in vi...